【产品概况】
产品名称:Human Complement C5 Antibody (Tesidolumab, Research Use)
产品编号:NBR-0890
针对靶点:Complement C5
抗体药商品名:Tesidolumab
抗体药描述:Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation), with a half-life in humans of approximately 9 days. Tesidolumab blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C5
Synonyms: C5a; C5b; CPAMD4
Target Description: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Ensembl: ENSG00000106804
Uniprot: P01031