产品名称：Human TNFRSF5 / CD40 Antibody (Lucatumumab, Research Use)
产品编号：NBR-0907
针对靶点：TNFRSF5 / CD40
抗体药商品名：Lucatumumab
抗体药描述：Lucatumumab is a fully humanised recombinant anti-CD40 mAb of the IgG1 isotype that blocks interaction of CD40 with its ligand CD40L inhibiting CD40L-mediated proliferation of normal B cells, CLL cells and non-Hodgkin lymphoma cells. The IgG1 antibody also mediates antibody-dependent cell-mediated cytotoxicity (ADCC). 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: CD40
Synonyms: Bp50; p50; TNFRSF5
Target Description: This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. 
Ensembl: ENSG00000101017
Uniprot: P25942