Human ACVR2B Antibody (Bimagrumab, Research Use)

产品名称	Human ACVR2B Antibody (Bimagrumab, Research Use)
目录号	NBR-0095
别名	ActR-IIB
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0095-100UG	100ug	￥550	请咨询
NBR-0095-1MG	1mg	￥3500	请咨询
NBR-0095-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human ACVR2B Antibody (Bimagrumab, Research Use)
产品编号：NBR-0095
针对靶点：ACVR2B
抗体药商品名：Bimagrumab
抗体药描述：Bimagrumab (BYM338) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. On August 20, 2013, it was announced that bimagrumab had received a breakthrough therapy designation for sporadic inclusion body myositis (sIBM) by the US Food and Drug Administration.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: ACVR2B
Synonyms: ActR-IIB
Target Description: Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c).
Ensembl: ENSG00000114739
Uniprot: Q13705