产品名称：Human CLDN6 Antibody (IMAB027, Research Use)
产品编号：NBR-0150
针对靶点：CLDN6
抗体药商品名：IMAB027
抗体药描述：IMAB027 is a monoclonal antibody that binds to CLDN6. Preclinically IMAB027 was shown to inhibit tumor growth and to kill cancer cells by antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. This trial is a first-in-human dose escalation and dose finding Phase 1 trial of IMAB027 in patients with recurrent advanced ovarian cancer to assess the safety and tolerability, the pharmacokinetics, the antitumoral activity and the immunogenicity of IMAB027. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: CLDN6
Synonyms: Skullin
Target Description: CLDN6 (Claudin 6) is a Protein Coding gene. Diseases associated with CLDN6 include Hepatitis C Virus and Hepatitis C. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling and Cell junction organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN9.
Ensembl:  ENSG00000184697
Uniprot:  ENSG00000184697