【产品概况】
产品名称:Human DKK1 Antibody (BHQ-880, Research Use)
产品编号:NBR-0161
针对靶点:DKK1
抗体药商品名:BHQ-880
抗体药描述:BHQ880 (Novartis) is a human neutralizing IgG1 anti-DKK1 monoclonal antibody that is being investigated for the prevention of SREs relating to MM and as an agent with potential anti-myeloma activity, with favourable preclinical results demonstrated in vitro.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: DKK1
Synonyms: SK
Target Description: DKK1 (Dickkopf WNT Signaling Pathway Inhibitor 1) is a Protein Coding gene. Diseases associated with DKK1 include Chiari Malformation Type I and Osteoporosis, Juvenile. Among its related pathways are ncRNAs involved in Wnt signaling in hepatocellular carcinoma and Alzheimer's disease and miRNA effects. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and low-density lipoprotein particle receptor binding.
Ensembl: ENSG00000107984
Uniprot: O94907