【产品概况】
产品名称:Human GCGR Antibody (Volagidemab, Research Use)
产品编号:NBR-0183
针对靶点:GCGR
抗体药商品名:Volagidemab
抗体药描述:Volagidemab (formerly REMD 477) is a fully human antibody that specifically binds to and blocks the glucagon receptor functions, being developed by REMD.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: GCGR
Synonyms: GGR
Target Description: GCGR (Glucagon Receptor) is a Protein Coding gene. Diseases associated with GCGR include Mahvash Disease and Hypoglycemia. Among its related pathways are Activation of cAMP-Dependent PKA and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and guanyl-nucleotide exchange factor activity. An important paralog of this gene is GIPR.
Ensembl: ENSG00000215644
Uniprot: P47871