产品名称：Human GPR49 Antibody (BNC101, Research Use)
产品编号：NBR-0191
针对靶点：GPR49
抗体药商品名：BNC101
抗体药描述：BNC101 is a first-in-class humanised monoclonal antibody that targets cancer stem cells (CSC). BNC101 binds to a receptor that is overexpressed on CSC in solid tumours including colorectal, breast, pancreatic, ovarian, lung, liver and gastric cancers. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: GPR49
Synonyms: LGR5; FEX; GPR49; GPR67; HG38
Target Description: LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene. Diseases associated with LGR5 include Ankyloglossia With Or Without Tooth Anomalies and Mucositis. Among its related pathways are Signaling by WNT and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is LGR6.
Ensembl: ENSG00000139292
Uniprot: O75473