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产品名称 Human MUC1 Antibody (Clivatuzumab, Research Use)
目录号 NBR-0250
别名 ADMCKD; ADMCKD1; CD227; MCD; MCKD; MCKD1; PEM; PUM
外观 Transparent Liquid
分子量 150kDa
CAS N/A
溶解度 Water, PBS, TBS Buffer,etc.
存储条件 Temp. -80℃
保存时间 see COA
备注1 CHO Expressed
备注2 Ab. Isotype - IgG
目录号 规格 价格 库存状态  
NBR-0250-100UG 100ug ¥550 请咨询
NBR-0250-1MG 1mg ¥3500 请咨询
NBR-0250-5MG 5mg ¥7500 请咨询



【产品概况】
产品名称:Human MUC1 Antibody (Clivatuzumab, Research Use)
产品编号:NBR-0250
针对靶点:MUC1
抗体药商品名:Clivatuzumab
抗体药描述:Yttrium (90 Y) Clivatuzumab Tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody-drug conjugate (ADC) designed by Immunomedics, Inc. for the treatment of pancreatic cancer. The antibody part, clivatuzumab (also known as PAM4), which targets mucin 1 (MUC1), is conjugated with the chelating agent 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid (DOTA), tetraxetan, and radiolabeled with the beta-emitting radioisotope Yttrium-90, a radioisotope which destroys the tumor cells.

【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG

 
【基因信息】
Gene Name: MUC1
Synonyms: ADMCKD; ADMCKD1; CD227; MCD; MCKD; MCKD1; PEM; PUM
Target Description: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
Ensembl: ENSG00000185499 
Uniprot: P15941
 
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