产品名称：Human ADAMTS5 Antibody (M6495, Research Use)
产品编号：NBR-0340
针对靶点：ADAMTS5
抗体药商品名：M6495
抗体药描述：M6495 is an anti-catabolic, bivalent, bifunctional Nanobody® that selectively inhibits ADAMTS-5 in vitro, reducing aggrecan cleavage.. M6495 is potent anti-catabolic drug which inhibits aggrecan and type II collagen degradation in both bovine and human cartilage explant cultures and bovine synovial co-cultures. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: ADAMTS5
Synonyms: ADAMTS11; ADMP-2
Target Description: Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN.
Ensembl: ENSG00000154736 
Uniprot: Q9UNA0