产品名称：Human HtrA1 Antibody (FHTR2163, Research Use)
产品编号：NBR-0392
针对靶点：HtrA1
抗体药商品名：FHTR2163
抗体药描述：FHTR2163 is an antigen-binding fragment of a humanized immunoglobulin G1 monoclonal antibody directed against high-temperature requirement A serine peptidase 1 (HTRA1) that is being developed as a potential intravitreal (ITV) treatment for patients with geographic atrophy (GA), an advanced form of dry age-related macular degeneration. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: HtrA1
Synonyms: ARMD7; HtrA; IGFBP5-protease; PRSS11
Target Description: Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin.
Ensembl: ENSG00000166033
Uniprot: Q92743