【产品概况】
产品名称:Human CD28 Antibody (Lulizumab, Research Use)
产品编号:NBR-0397
针对靶点:CD28
抗体药商品名:Lulizumab
抗体药描述:Lulizumab pegol is a humanised PEGylated anti-CD28 antibody-based biologic, developed as a potential treatment for autoimmune diseases. This so-called domain antibody (dAb) contains the smallest functional binding unit and lacks the divalent structure characteristic of a complete antibody . PEGylation improves solubility and extends circulating half-life .
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD28
Synonyms:
Target Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.
Ensembl: ENSG00000178562
Uniprot: P10747