【产品概况】
产品名称:Human uPAR Antibody (ATN-658, Research Use)
产品编号:NBR-0403
针对靶点:uPAR
抗体药商品名:ATN-658
抗体药描述:ATN-658, a mouse IgG1, is able to bind to D2D3 of uPAR with high affinity (Kd ∼ 1 nM), does not inhibit the binding of uPA to uPAR, and is able to bind to uPAR even when uPA was also bound.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: uPAR
Synonyms: PLAUR; CD87; URKR
Target Description: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Ensembl: ENSG00000011422
Uniprot: Q03405