产品名称：Human Notch3 Antibody (Tarextumab, Research Use)
产品编号：NBR-0436
针对靶点：Notch3
抗体药商品名：Tarextumab
抗体药描述：Tarextumab (formerly OMP-59R5) is a fully human monoclonal antibody targeting the Notch 2/3 receptors. It is being tested as a possible treatment for cancer. In January 2015, the US FDA granted orphan drug designation to tarextumab for the treatment of pancreatic cancer and lung cancer. Two early stage clinical trials have reported encouraging results. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: Notch3
Synonyms: CADASIL; CASIL
Target Description: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination 1.
Ensembl: ENSG00000074181
Uniprot: Q9UM47