【产品概况】
产品名称:Human TREM-1 Antibody (PY159, Research Use)
产品编号:NBR-0458
针对靶点:TREM-1
抗体药商品名:PY159
抗体药描述:PY159 is a humanized monoclonal antibody (mAb) that specifically binds Triggering receptor expressed on myeloid cells 1 (TREM1) and acts as an agonist mAb by crosslinking TREM1 and inducing downstream signaling through the TREM1/DNAX Activating Protein of 12kDa (DAP12) complex.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TREM-1
Synonyms: CD354; TREM-1
Target Description: Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12.
Ensembl: ENSG00000124731
Uniprot: Q9NP99