Human DR5 / TRAILR2 Antibody (Drozitumab, Research Use)

产品名称	Human DR5 / TRAILR2 Antibody (Drozitumab, Research Use)
目录号	NBR-0463
别名	CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB; TNFRSF10B
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0463-100UG	100ug	￥550	请咨询
NBR-0463-1MG	1mg	￥3500	请咨询
NBR-0463-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human DR5 / TRAILR2 Antibody (Drozitumab, Research Use)
产品编号：NBR-0463
针对靶点：DR5 / TRAILR2
抗体药商品名：Drozitumab
抗体药描述：Drozitumab is a human monoclonal antibody in development for the treatment of cancers. It targets Tumour Necrosis Factor Related Apoptosis-inducing Ligand (TRAIL), whose receptors are found on the surface of many types of malignant cells.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: DR5 / TRAILR2
Synonyms: CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB; TNFRSF10B
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Ensembl: ENSG00000120889
Uniprot: O14763