【产品概况】
产品名称:Human FcgR3a / CD16a Antibody (AFM13, Research Use)
产品编号:NBR-0489
针对靶点:FcgR3a / CD16a
抗体药商品名:AFM13
抗体药描述:AFM13 is a tetravalent bispecific chimeric (anti-human CD30 x anti-human CD16A) recombinant antibody construct which is being developed to treat CD30-positive malignancies.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FcgR3a
Synonyms: CD16; CD16a; FCG3; FCGR3
Target Description: Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).
Ensembl: ENSG00000203747
Uniprot: P08637