Human ANGPT2 Antibody (Zansecimab, Research Use)

产品名称	Human ANGPT2 Antibody (Zansecimab, Research Use)
目录号	NBR-0510
别名	Ang2
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0510-100UG	100ug	￥550	请咨询
NBR-0510-1MG	1mg	￥3500	请咨询
NBR-0510-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human ANGPT2 Antibody (Zansecimab, Research Use)
产品编号：NBR-0510
针对靶点：ANGPT2
抗体药商品名：Zansecimab
抗体药描述：Zansecimab is a humanized IgG4 isotype antibody that neutralizes phospho-Tie2 induction due to Ang2, thereby stopping angiogenesis. The mechanism behind the neutralization is due to the antibody binding with high affinity to, and inhibiting Ang2.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: ANGPT2
Synonyms: Ang2
Target Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.
Ensembl: ENSG00000091879
Uniprot: O15123