【产品概况】
产品名称:Human PTK7 / CCK4 Antibody (Cofetuzumab, Research Use)
产品编号:NBR-0552
针对靶点:PTK7 / CCK4
抗体药商品名:Cofetuzumab
抗体药描述:PF-06647020 (cofetuzumab pelidotin) is a humanized, anti-PTK7 antibody–drug conjugate, designed to deliver an auristatin microtubule inhibitor payload (Aur0101) into target cells. It was shown to induce prolonged tumor regression in patient-derived, tumor xenograft preclinical models.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PTK7
Synonyms: CCK4
Target Description: Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
Ensembl: ENSG00000112655
Uniprot: Q13308