产品名称：Human Amyloid Beta Antibody (Donanemab, Research Use)
产品编号：NBR-0589
针对靶点：Amyloid Beta
抗体药商品名：Donanemab
抗体药描述：Donanemab, aka N3pG, is a humanized IgG1 monoclonal antibody developed from mouse mE8-IgG2a. This biologic drug recognizes Aβ(p3-42), a pyroglutamate form of Aβ that is aggregated in amyloid plaques. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: Amyloid Beta
Synonyms: Alpha-SAPP; AD1
Target Description: APP (Amyloid Beta Precursor Protein) is a Protein Coding gene. Diseases associated with APP include Cerebral Amyloid Angiopathy, App-Related and Alzheimer Disease, Familial, 1. Among its related pathways are MyD88 dependent cascade initiated on endosome and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include identical protein binding and enzyme binding. An important paralog of this gene is APLP2.
Ensembl:  ENSG00000142192
Uniprot:  P05067