【产品概况】
产品名称:Human TNFSF2 / TNFa Antibody (Golimumab, Research Use)
产品编号:NBR-0664
针对靶点:TNFSF2 / TNFa
抗体药商品名:Golimumab
抗体药描述:Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TNFSF2
Synonyms: TNF-Alpha; TNFSF2; TNFA; DIF
Target Description: TNF (Tumor Necrosis Factor) is a Protein Coding gene. Diseases associated with TNF include Malaria and Asthma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TNFR1 Pathway.
Ensembl: ENSG00000232810
Uniprot: P01375