产品名称：Human BTLA / CD272 Antibody (Icatolimab, Research Use)
产品编号：NBR-0669
针对靶点：BTLA / CD272
抗体药商品名：Icatolimab
抗体药描述：Icatolimab is a humanized IgG4 monoclonal antibody (mAb) with a hinge mutation (S228P) that binds BTLA and blocks its interaction with its ligand HVEM. In preclinical studies, icatolimab monotherapy suppressed tumor growth in murine tumor models using human BTLA knock-in mice. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: BTLA
Synonyms: BTLA1; CD272
Target Description: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Ensembl: ENSG00000186265
Uniprot: Q7Z6A9