产品名称：Human B7-H1 / PD-L1 / CD274 Antibody (Lodapolimab, Research Use)
产品编号：NBR-0699
针对靶点：B7-H1 / PD-L1 / CD274
抗体药商品名：Lodapolimab
抗体药描述：Lodapolimab is a fully human immunoglobulin G 1 lambda (IgG1λ) monoclonal antibody that binds to human PD-L1 expressed on tumour cells and tumor-infiltrating immune cells, prevents its binding to two receptors PD-1 and CD80 (B7-1), on the T cells. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name:  CD274
Synonyms: B7-H; B7-H1; B7H1; PD-L1; PDCD1LG1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7