产品名称：Human Hepcidin / HAMP Antibody (LY2787106, Research Use)
产品编号：NBR-0705
针对靶点：Hepcidin / HAMP
抗体药商品名：LY2787106
抗体药描述：LY2787106 is a fully humanized mAb with high affinity for human hepcidin. This phase 1 study evaluated the safety, PK/PD, and efficacy (effects on serum iron panel [iron, ferritin, transferrin saturation (TSAT), soluble transferrin receptor, reticulocyte hemoglobin], reticulocytosis, and hemoglobin [Hb]) of LY2787106 in cancer pts with anemia. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: HAMP 
Synonyms: HEPC; HFE2B; LEAP-1; LEAP1
Target Description: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma.
Ensembl: ENSG00000105697
Uniprot: P81172