产品名称：Human ICOS / CD278 Antibody (MEDI-570, Research Use)
产品编号：NBR-0715
针对靶点：ICOS / CD278
抗体药商品名：MEDI-570
抗体药描述：MEDI-570 is an afucosylated human IgG1κ mAb, directed against the ligand binding domain of human ICOS. MEDI-570 displays relatively high (picomolar) binding to ICOS, which abrogates ICOS-mediated T cell proliferation and cytokine production. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: ICOS
Synonyms: AILIM; CD278; CVID1
Target Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
Ensembl: ENSG00000163600
Uniprot: Q9Y6W8