
【产品概况】
产品名称:Human IFNg Antibody (Emapalumab, Research Use)
产品编号:NBR-0717
针对靶点:IFNg
抗体药商品名:Emapalumab
抗体药描述:Emapalumab is a fully human immunoglobulin G1 monoclonal antibody directed against interferon-γ (IFN-γ), which in November 2018 received the first global approval for the treatment of pediatric and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent, or progressive disease or intolerance to HLH therapy.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IFN
Synonyms: GIMD69; IFG; IFI
Target Description: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.
Ensembl: ENSG00000111537
Uniprot: P01579