产品名称：Human PDCD1 / PD-1 / CD279 Antibody (Nofazinlimab, Research Use)
产品编号：NBR-0739
针对靶点：PDCD1 / PD-1 / CD279
抗体药商品名：Nofazinlimab
抗体药描述：Nofazinlimab is a humanized recombinant IgG4 monoclonal antibody targeting human programmed cell death protein 1 (PD-1) being developed in solid tumors. Nofazinlimab shows comparable high binding affinities to the PD-1 of humans, cynomolgus monkey, and mouse, and can block the interaction of PD-1 with its ligands PD-L1 and PD-L2. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: PDCD1
Synonyms: CD279; hSLE1; PD-1; PD1; SLEB2
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2. 
Ensembl: ENSG00000188389
Uniprot: Q15116