
【产品概况】
产品名称:Human LAG3 / CD223 Antibody (Fianlimab, Research Use)
产品编号:NBR-0789
针对靶点:LAG3 / CD223
抗体药商品名:Fianlimab
抗体药描述:Fianlimab is a fully human monoclonal antibody targeting the immune checkpoint receptor LAG-3 on T cells and was invented using Regeneron's proprietary VelocImmune® technology. In melanoma, LAG-3 expression on cancer cells is associated with therapeutic resistance to PD-1 inhibitors.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: LAG3
Synonyms: CD223
Target Description: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1 (By similarity).
Ensembl: ENSG00000089692
Uniprot: P18627