产品名称：Human MUC18 / MCAM / CD146 Antibody (Imaprelimab, Research Use)
产品编号：NBR-0806
针对靶点：MUC18 / MCAM / CD146
抗体药商品名：Imaprelimab
抗体药描述：Imaprelimab (PRX-003) is an anti-MCAM mAb developed as a novel therapy for psoriasis. In patients with autoimmune diseases, a subset of MCAM+ve T cells (which have an effector memory T-helper 17 phenotype) produce high levels of pro-inflammatory IL-17. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name:  MCAM
Synonyms: CD146; HEMCAM; MelCAM; METCAM; MUC18
Target Description: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. 
Ensembl: ENSG00000076706
Uniprot: P43121