Product Name:

NebuSelect™ Recombinant Human PKC iota, His-tag

Catalog#:

NBL-240459

Description:

NebuSelect™ Recombinant Human PKC iota, His-tag(Cat#NBL-240459) is expressed in Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met10-Val596.

Species:

Human

Expression System:

Baculovirus-Insect Cells

Molecular Weight: 

The protein has a predicted MW of 68.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

Target Name:

PKC iota

Target Information:

PKClambda/iota belongs to the third group of the PKC family, atypical PKC (aPKC), together with PKCzeta based on its sequence divergence from conventional and novel PKCs observed not only in the N-terminal regulatory domain but also in the kinase domain. Although one of the most distinct features of aPKC is its single, unrepeated cysteine-rich domain, recent studies have revealed that the N-terminal regulatory domain has additional aPKC-specific structural motifs involved in various protein-protein interactions, which are important for the regulation and the subcellular targeting of aPKC.

Amino Acid Sequence: 

Met10-Val596

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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