产品名称 | NebuSelect™ Recombinant Human PBK/TOPK, His-tag |
---|---|
目录号 | NBL-240460 |
别名 | PBK/TOPK |
外观 | see COA |
分子量 | Met1-Val322 |
CAS | N/A |
溶解度 | Water Soluble |
存储条件 | Short term 4℃; Long term -20℃. |
保存时间 | 2 years |
备注1 | Q96KB5-1 |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
NBL-240460-100ug | 100ug | Inquire | Inquire | |
NBL-240460-1mg | 1mg | Inquire | Inquire | |
NBL-240460-Customized Size | N/A | Inquire | Inquire |
Product Name:
NebuSelect™ Recombinant Human PBK/TOPK, His-tag
Catalog#:
NBL-240460
Description:
NebuSelect™ Recombinant Human PBK/TOPK, His-tag(Cat#NBL-240460) is expressed in Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met1-Val322.
Species:
Human
Expression System:
Baculovirus-Insect Cells
Molecular Weight:
The protein has a predicted MW of 37.61 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.
Target Name:
PBK/TOPK
Target Information:
T-lymphokine-activated killer cell-originated protein kinase (TOPK, also known as PDZ-binding kinase or PBK) plays a crucial role in cell cycle regulation and mitotic progression. Abnormal overexpression or activation of TOPK has been observed in many cancers, including colorectal cancer, triple-negative breast cancer, and melanoma, and it is associated with increased development, dissemination, and poor clinical outcomes and prognosis in cancer. Moreover, TOPK phosphorylates p38, JNK, ERK, and AKT, which are involved in many cellular functions, and participates in the activation of multiple signaling pathways related to MAPK, PI3K/PTEN/AKT, and NOTCH1.
Amino Acid Sequence:
Met1-Val322
Purity:
>95%
Formulation:
see COA
Endotoxin:
<1EU/ug(LAL Method)
Storage:
4°C for short term.
-20°C for long term.
To get more information, please contact us freely.