Product Name:

NebuSelect™ Recombinant Biotinylated Human FLT3/Flk-2, Avi-His-tag

Catalog#:

NBL-240468

Description:

NebuSelect™ Recombinant Biotinylated Human FLT3/Flk-2, Avi-His-tag(Cat#NBL-240468) is expressed in CHO with His tag and Avi tag at the C-Terminus.It contains Asn27-Asn541.

Species:

Human

Expression System:

CHO

Molecular Weight: 

The protein has a predicted MW of 61.20 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

FLT3/Flk-2

Target Information:

The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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