Product Name:

NebuSelect™ Recombinant Human IDH1, His-tag

Catalog#:

NBL-240579

Description:

NebuSelect™ Recombinant Human IDH1, His-tag(Cat#NBL-240579) is expressed in E.coli with His tag at the C-Terminus.It contains Ser2-Leu414.

Species:

Human

Expression System:

E.coli

Molecular Weight: 

The protein has a predicted MW of 47.35 kDa same as Bis-Tris PAGE result.

Target Name:

IDH1

Target Information:

Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.

Amino Acid Sequence: 

Ser2-Leu414

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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