Product Name:

NebuSelect™ Recombinant SARS PLpro/papain-like protease, Avi-His-tag

Catalog#:

NBL-240614

Description:

NebuSelect™ Recombinant SARS PLpro/papain-like protease, Avi-His-tag(Cat#NBL-240614) is expressed in E.coil with His tag and Avi tag at the N-Terminus.It contains Glu1-Ile314.

Species:

SARS

Expression System:

E.coli

Molecular Weight: 

The protein has a predicted MW of 38.6 kDa same as Bis-Tris PAGE result.

Target Name:

PLpro/papain-like protease; Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro

Target Information:

The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Amino Acid Sequence: 

Glu1-Ile314

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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