Product Name:

NebuSelect™ Recombinant Cynomolgus MASP2, His-tag

Catalog#:

NBL-240629

Description:

NebuSelect™ Recombinant Cynomolgus MASP2, His-tag(Cat#NBL-240629) is expressed in E.coli with His tag at the C-Terminus.It contains Thr287-Phe686.

Species:

Cynomolgus

Expression System:

E.coli

Molecular Weight: 

The protein has a predicted MW of 46.8 kDa. Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Bis-Tris PAGE result.

Target Name:

MASP2; MAP19; MASP-2; MASP1P1; sMap

Target Information:

The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

Amino Acid Sequence: 

Thr287-Phe686

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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