Product Name:

NebuSelect™ Recombinant Human Wnt Surrogate-Fc Fusion, hFc-tag

Catalog#:

NBL-240683

Description:

NebuSelect™ Recombinant Human Wnt Surrogate-Fc Fusion, hFc-tag(Cat#NBL-240683) is expressed in HEK293 with hFc tag at the C-Terminus.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 58.50 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.

Target Name:

Wnt Surrogate-Fc FusionSpeciesHuman

Target Information:

Wnt-3a is regarded as an activator of the canonical Wnt signaling pathway. This activator is expressed in the dorsal midline region and is responsible for spinal cord development. In addition, Wnt-3a plays a regulatory role in autophagy, apoptosis, and regeneration of neurons, neurogenic inflammation and axon regeneration.Wnt-3a promotes the beta-catenin/Tcf pathway which is tumor inducing and can cause cancer when expressed in particular cell populations. It is also one of the most commonly used cytokines for organoid construction.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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