Product Name:

NebuSelect™ Recombinant Human CLEC9A, hFc-tag

Catalog#:

NBL-240689

Description:

NebuSelect™ Recombinant Human CLEC9A, hFc-tag(Cat#NBL-240689) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Lys57-Val241.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 48.5 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Target Name:

CLEC9A; CD370; CLEC9A; 9830005G06Rik; DNGR-1; HEEE9341; UNQ9341

Target Information:

CLEC9A expression was significantly higher in psoriatic skin compared with healthy donor. In psoriatic skin and PsA ST, CLEC9A() cells were in close proximity to TUNEL() cells. SF CLEC9A levels were significantly lower compared with paired PsA serum. Adalimumab treatment did not affect CLEC9A serum level and skin expression. The downregulation of synovial CLEC9A might be associated with a novel mechanism by which anti-TNF therapy might reduce CD8-mediated inflammation in PsA patients.

Amino Acid Sequence: 

Lys57-Val241

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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