Product Name:

NebuSelect™ Recombinant Cynomolgus IL-22R alpha 1, His-tag

Catalog#:

NBL-240694

Description:

NebuSelect™ Recombinant Cynomolgus IL-22R alpha 1, His-tag(Cat#NBL-240694) is expressed in HEK293 with His tag at the C-Terminus.It contains Pro18-Thr225.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 24.84 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.

Target Name:

IL-22R alpha 1

Target Information:

IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Amino Acid Sequence: 

Pro18-Thr225

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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