Product Name:

NebuSelect™ Recombinant Human DSG3, His-tag

Catalog#:

NBL-240712

Description:

NebuSelect™ Recombinant Human DSG3, His-tag(Cat#NBL-240712) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu50-Arg615.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 64 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.

Target Name:

DSG3; Desmoglein-3; PVA; CDHF6; SG3; DSG3

Target Information:

To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.

Amino Acid Sequence: 

Glu50-Arg615

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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