Product Name:

NebuSelect™ Recombinant Cynomolgus LILRB4/CD85k/ILT3, His-tag

Catalog#:

NBL-240762

Description:

NebuSelect™ Recombinant Cynomolgus LILRB4/CD85k/ILT3, His-tag(Cat#NBL-240762) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln22-Glu259.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 27.2 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Bis-Tris PAGE result.

Target Name:

LILRB4/CD85k/ILT3; HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K

Target Information:

LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

Amino Acid Sequence: 

Gln22-Glu259

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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