Product Name:

NebuSelect™ Recombinant Human LOX1, His-tag

Catalog#:

NBL-240844

Description:

NebuSelect™ Recombinant Human LOX1, His-tag(Cat#NBL-240844) is expressed in HEK293 with His tag at the N-Terminus.It contains Ser61-Gln273.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 25.4 kDa. Due to glycosylation, the protein migrates to 30-36 kDa under reduced condition and 60-70 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.

Target Name:

LOX1; Ox-LDL receptor 1; LOX-1; CLEC8A; LOX1; OLR1; LOXIN; SR-E1; SCARE1; SLOX1

Target Information:

LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.

Amino Acid Sequence: 

Ser61-Gln273

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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