Product Name:

NebuSelect™ Recombinant Human LAIR1/CD305, Avi-His-tag

Catalog#:

NBL-240847

Description:

NebuSelect™ Recombinant Human LAIR1/CD305, Avi-His-tag(Cat#NBL-240847) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-His163.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 18.2 kDa. Due to glycosylation, the protein migrates to 30-36 kDa based on Bis-Tris PAGE result.

Target Name:

LAIR1/CD305; CD305; HLAIR1; LAIR1; LAIR-1

Target Information:

LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.

Amino Acid Sequence: 

Gln22-His163

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.