Product Name:

NebuSelect™ Recombinant Biotinylated Human IgE, Avi-His-tag

Catalog#:

NBL-240913

Description:

NebuSelect™ Recombinant Biotinylated Human IgE, Avi-His-tag(Cat#NBL-240913) is expressed in HEK293 with His and Avi tag at the C-Terminus.It contains Cys209-Lys428.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 27.8 kDa. Due to glycosylation, the protein migrates to 32-38 kDa based on Bis-Tris PAGE result.

Target Name:

IgE

Target Information:

Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

Amino Acid Sequence: 

Cys209-Lys428

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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