Product Name:

NebuSelect™ Recombinant Human Aggrecan, His-tag

Catalog#:

NBL-240940

Description:

NebuSelect™ Recombinant Human Aggrecan, His-tag(Cat#NBL-240940) is expressed in HEK293 with His tag at the C-Terminus.It contains Ala17-Leu721.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 78.86 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.

Target Name:

Aggrecan

Target Information:

Aggrecan is a large proteoglycan that forms giant hydrated aggregates with hyaluronan in the extracellular matrix (ECM). The extraordinary resistance of these aggregates to compression explains their abundance in articular cartilage of joints where they ensure adequate load-bearing. In the brain, they provide mechanical buffering and contribute to formation of perineuronal nets, which regulate synaptic plasticity. Aggrecan is also present in cardiac jelly, developing heart valves, and blood vessels during cardiovascular development. Whereas aggrecan is essential for skeletal development, its function in the developing cardiovascular system remains to be fully elucidated.

Amino Acid Sequence: 

Ala17-Leu721

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.