Product Name:

NebuSelect™ Recombinant Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, Avi-His-tag

Catalog#:

NBL-240941

Description:

NebuSelect™ Recombinant Biotinylated Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, Avi-His-tag(Cat#NBL-240941) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 108.77 kDa(ITGAV)&80.84 kDa(ITGB3). Due to glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.

Target Name:

Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer

Target Information:

ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Amino Acid Sequence: 

Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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