Product Name:

NebuSelect™ Recombinant Cynomolgus VSIG4, His-tag

Catalog#:

NBL-240944

Description:

NebuSelect™ Recombinant Cynomolgus VSIG4, His-tag(Cat#NBL-240944) is expressed in HEK293 with His tag at the C-Terminus.It contains Arg25-Ala288.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 30.16 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.

Target Name:

VSIG4

Target Information:

VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.

Amino Acid Sequence: 

Arg25-Ala288

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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