Product Name:

NebuSelect™ Recombinant Human Kremen-1, hFc-tag

Catalog#:

NBL-240996

Description:

NebuSelect™ Recombinant Human Kremen-1, hFc-tag(Cat#NBL-240996) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Arg21-Thr392.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 67.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

Kremen-1; Kremen protein 1; KREMEN; KRM1; KREMEN1

Target Information:

KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.

Amino Acid Sequence: 

Arg21-Thr392

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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