Product Name:

NebuSelect™ Recombinant Human GPVI, His-tag

Catalog#:

NBL-241018

Description:

NebuSelect™ Recombinant Human GPVI, His-tag(Cat#NBL-241018) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln21-Lys267.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 28 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:

GPVI; GPVI; Gp6; Glycoprotein 6; MGC138168

Target Information:

Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.

Amino Acid Sequence: 

Gln21-Lys267

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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