Product Name:

NebuSelect™ Recombinant Human-AREG, hFc-tag

Catalog#:

NBL-241058

Description:

NebuSelect™ Recombinant Human-AREG, hFc-tag(Cat#NBL-241058) is expressed in HEK293 with hFc tag at the N-terminus.It contains Ser101-Lys187.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 37.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.

Target Name:

AREG; Amphiregulin; AR; SDGF; AREG; AREGB; CRDGF; MGC13647

Target Information:

Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.

Amino Acid Sequence: 

Ser101-Lys187

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.