Product Name:

NebuSelect™ Recombinant Human LRP-6, mFc-tag

Catalog#:

NBL-241062

Description:

NebuSelect™ Recombinant Human LRP-6, mFc-tag(Cat#NBL-241062) is expressed in HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ala20-Pro630.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 95.32 kDa. Due to glycosylation, the protein migrates to 97-110 kDa based on Bis-Tris PAGE result.

Target Name:

LRP-6

Target Information:

Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin.

Amino Acid Sequence: 

Ala20-Pro630

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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