Product Name:

NebuSelect™ Recombinant Human ACVR1B/Activin RIB, hFc-tag

Catalog#:

NBL-241067

Description:

NebuSelect™ Recombinant Human ACVR1B/Activin RIB, hFc-tag(Cat#NBL-241067) is expressed in HEK293 with hFc tag at the C-terminus.It contains Ser24-Glu126.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 37.36 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.

Target Name:

ACVR1B/Activin RIB

Target Information:

Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Moreover, ACVR1 has been extensively studied for its causal role in fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder characterised by progressive heterotopic ossification. ACVR1 is linked to different pathologies, including cardiac malformations and alterations in the reproductive system.

Amino Acid Sequence: 

Ser24-Glu126

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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